A man suffered multiple serious injuries after a head-on crash on Friday evening.
At around 6.30pm, a dark grey Renault Clio was travelling on the Windsor Road northbound towards Slough.
It crashed head-on into a light blue Honda Jazz travelling in the opposite direction towards Eton.
A 61-year-old man who was driving the Honda suffered multiple serious injuries including a broken leg and a number of broken ribs.
He was taken to the John Radcliffe Hospital in Oxford for treatment, where he remains at this time.
The driver of the Renault suffered minor injuries.
A 31-year-old man from Slough was arrested on suspicion of causing serious injury by dangerous driving and driving a motor vehicle when alcohol level is above the limit.
He has since been released under investigation.
Investigating officer PC Ben Taylor of the Joint Operations Unit for Roads Policing, based at Taplow, said: “This was a serious collision that occurred at a busy time of the evening on Friday.
“I am appealing to anybody who was in the area of Windsor Road in Slough and witnessed the collision, or saw either vehicle prior to the collision to please make contact with police.
“I am particularly keen to hear from anybody who may have dash-cam footage of the collision to please check this and get in touch if it has captured anything that can assist this investigation.
“You can contact police by calling the 24-hour non-emergency number 101, quoting reference number 43200351500, or by making a report online.
“Alternatively, for 100% anonymity, you can also call the independent charity Crimestoppers on 0800 555 111.”